January 2019 Newly Funded Projects

​The table below covers newly awarded grants from our January 2019 grant cycle, totaling nearly $4.15M, that are funded in partnership with the EB Medical Research Foundation and Cure EB.

INSTITUTION	PROJECT NAME	PRINCIPAL INVESTIGATOR(S)	AMOUNT AWARDED
​PolarityTE	Genetic modification of a commercially available Autologous Homologous Skin Construct for permanent epidermal replacement in Recessive Dystrophic Epidermolysis Bullosa	Nikolai Sopko MD PhD	​$300,000
​Columbia University	Development of a drug testing platform for recessive dystrophic epidermolysis bullosa squamous cell carcinoma using induced pluripotent cancer cells	Joanna Jackow PhD	$551,250
​Neem Biotech Limited	Identification of ajoene analogues for the treatment of epidermolysis bullosa	Tracy Nevitt PhD	​$112,400
​Thomas Jefferson University	Targeting fibrosis for RDEB therapy in preclinical animal models	Andrew South PhD	$159,054
​University of Colorado	A Comprehensive Stem Cell Biobank for EB Patients	Ganna Bilousova PhD Anna L. Bruckner MD Dennis R Roop PhD Igor Kogut PhD	$286,815
University of Minnesota	Next Generation Genome Editing for RDEB	Jakub Tolar MD PhD	$1,000,000
​University of Colorado	​A cGMP-Compliant Library Master Cell Bank as a Necessary Prerequisite for an iPSC-Based Clinical Trial for EB	​Igor Kogut PhD Ganna Bilousova PhD Dennis R Roop PhD	$964,176
​University of Colorado	Developing an iPS Cell-based Therapy for Epidermolysis Bullosa Simplex	Dennis R Roop PhD Ganna Bilousova PhD Igor Kogut PhD Anna Bruckner MD	​$518,638
​Université du Québec à Chicoutimi	Inactivation of epidermolysis bullosa simplex dominant mutations by allele-specific CRISPR/Cas9	Catherine Laprise PhD Lucie Germain PhD Jacques-P Tremblay PhD	​$255,400
Wings Therapeutics	Clinical Development of QR-313 for Treatment of RDEB	Deborah Ramsdell	$1,500,000