Two cities. One mission. Help fund a cure for Epidermolysis Bullosa (EB).
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Not from Seattle or San Diego? Anyone can enter to win the vedder cup jersey!
Donate. Pick Your Team.
Help Win the Vedder Cup city vs city challenge!
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in the lead for 13 days straight! |
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Not from Seattle or San Diego? Anyone can join! Pick a side and make an impact.
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Every newsletter sign up and donation enters you to win a one-of-a-kind Vedder Cup jersey.
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Tracker last updated: 10AM ET 4/27/2026
WIN A ONE-OF-A-KIND VEDDER CUP JERSey
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Only 10 exist. And one could be yours.
We created 10 custom Vedder Cup jerseys and each one will be personalized with the winner’s name. How winners are chosen:
How to enter:
Winners will be selected and notified on May 18 (the day after the final game of the series.) |
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No purchase or donation necessary to enter or win. Winners will be contacted via the information provided at donation. Additional terms may apply.
More Than a Rivalry.
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The Vedder Cup started as a fan-favorite rivalry between the Mariners and Padres, named after Eddie Vedder, who’s called both cities home. In 2025, it became official. Now, it’s something bigger. Every donation supports EB Research Partnership, the nonprofit founded by Eddie and Jill Vedder, funding research to treat and cure EB, a rare and life-threatening skin disease. |
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The Reason We Show Up
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These are just a few of the incredible kids living with Epidermolysis Bullosa (EB) who were part of the Vedder Cup last year.
For them and their families, this isn’t just a game.
It’s progress. It’s hope. It’s the possibility of a future without pain.
Every donation helps move that future closer.
For them and their families, this isn’t just a game.
It’s progress. It’s hope. It’s the possibility of a future without pain.
Every donation helps move that future closer.
At EBRP, we know that in order to do things that haven’t been done you need to be willing to break the mold.
With this innovative business model we’re pioneering a new path forward that will not only revolutionize the way nonprofits operate, but also show the world how cures are found. We don’t just write checks and hope for the best. Instead, we operate like a venture capitalist with a focus on a different kind of ROI, return on impact. We create venture agreements with each project we fund. When those projects succeed, the returns are reinvested back into other promising research and development projects.
Did we mention the science we fund is also scalable across thousands of other rare diseases? That's right. The impact of every dollar invested at EBRP is multiplied many times over.
With this innovative business model we’re pioneering a new path forward that will not only revolutionize the way nonprofits operate, but also show the world how cures are found. We don’t just write checks and hope for the best. Instead, we operate like a venture capitalist with a focus on a different kind of ROI, return on impact. We create venture agreements with each project we fund. When those projects succeed, the returns are reinvested back into other promising research and development projects.
Did we mention the science we fund is also scalable across thousands of other rare diseases? That's right. The impact of every dollar invested at EBRP is multiplied many times over.
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Our Venture Philanthropy Model has been highlighted for its leadership by Harvard, Yale, MIT, the Milken Institute, Stanford Social Innovation Review, and more.
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With this business model we are actively transforming the EB landscape while creating scalable impact. These projects, this work, and the way we operate will create a butterfly effect for the 400M+ globally impacted by a rare disease.
Download our Impact Booklet to explore the Harvard Business School and Yale School of Management case studies on EBRP's innovative model and transformative impact.
Download our Impact Booklet to explore the Harvard Business School and Yale School of Management case studies on EBRP's innovative model and transformative impact.
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Children with EB are often called “Butterfly Children” because their skin is as fragile as the wings of a butterfly. With skin this fragile, everyday activities that many take for granted like eating, sleeping, walking and playing can become monumental tasks.
The harsh reality is that rare diseases affect more people than HIV and Cancer combined. EB is one of over 10,000 rare diseases, 95% of which have no approved treatments or cures. We are focused on finding a cure for EB, but for us that’s just the beginning. |
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Founded in 2010 by a group of dedicated parents, Jill Vedder, and Eddie Vedder of Pearl Jam, EB Research Partnership (EBRP) is the largest nonprofit funding research aimed at finding a cure for Epidermolysis Bullosa (EB).
Over the last decade, we have made remarkable strides, including raising +$60M for life-saving research, contributing to a 20x growth in EB clinical trials, helping to fund the first-ever FDA approved topical gene therapy and treatment for EB families. The progress we’ve made in EB is undeniable, however, we are only scratching the surface. Our Venture Philanthropy Model is actively transforming the EB landscape while creating scalable impact. These projects, this work, and the way we operate will create a butterfly effect for the 400M+ globally impacted by a rare disease. |
