EB Research Partnership
  • Epidermolysis Bullosa
    • What is EB?
    • Resources
    • Life with EB
  • Research
    • Funded Projects
    • Consortia
    • Clinical Trials
    • Scientific Advisory Board
    • Apply for a Grant
    • Community Council
  • Get Involved
    • Donate
    • Venture Into Cures
    • Sponsor
    • EBRP Events >
      • ACTion for Jackson
      • All in for a Cure
    • Endurance Events
    • Community Led Events
  • Media
    • Press
    • Videos
  • About Us
    • Our Mission
    • Financials
    • Venture Philanthropy
    • Supporter Spotlight
    • Leadership >
      • Board of Directors
      • Staff
  • Donate

Dystrophic EB (DEB)

Dystrophic EB (DEB) causes blistering in the dermis, the inner layer of the skin. Symptoms range from mild to severe. DEB is caused by mutations in the gene COL7A1, which holds the instructions to make the protein collagen 7. There are 2 main subtypes: Dominant (DDEB) and Recessive (RDEB). DDEB causes blistering generally on the hands, elbows, knees, and feet. RDEB causes blisters both on the skin and inside the body. Individuals with RDEB have an increased risk for squamous cell carcinoma, and their life expectancy is age 30. RDEB is considered one of the most severe forms of EB.

Life with Dystrophic eb

Meet Elodie: Click on her photo to read about her life with Dystrophic EB.
Picture
Back to "What is EB?"

Other EB Subtypes

Click below to learn about the other 3 major subtypes of Epidermolysis Bullosa: EB Simplex, Junctional EB, and Kindler Syndrome.
Picture
Picture
Picture

EB Research Partnership

132 East 43rd St, Suite 432
New York, NY 10017
info@ebresearch.org
646-844-0902
Careers

Contact Us
​

Donor Privacy Policy
Donate

​
Our Mission

​
Press
  • Epidermolysis Bullosa
    • What is EB?
    • Resources
    • Life with EB
  • Research
    • Funded Projects
    • Consortia
    • Clinical Trials
    • Scientific Advisory Board
    • Apply for a Grant
    • Community Council
  • Get Involved
    • Donate
    • Venture Into Cures
    • Sponsor
    • EBRP Events >
      • ACTion for Jackson
      • All in for a Cure
    • Endurance Events
    • Community Led Events
  • Media
    • Press
    • Videos
  • About Us
    • Our Mission
    • Financials
    • Venture Philanthropy
    • Supporter Spotlight
    • Leadership >
      • Board of Directors
      • Staff
  • Donate