EB Research Partnership
  • Epidermolysis Bullosa
    • What is EB?
    • Life with EB
    • Resources
  • Research
    • Our Impact
    • Scientific Advisory Board
    • Clinical Trials >
      • Filsuvez
      • Vyjuvek
      • ZEVASKYN
    • Town Halls
    • Apply for a Grant
  • Get Involved
    • Donate
    • Sponsor
    • EB Active
    • Events
    • The Effect
    • Shop
    • Give Cryptocurrency
    • Give Stocks
    • Give through Donor Advised Funds (DAF)
    • Accelerator Fund
  • Media
    • Matter of Time Film
    • Press
    • Videos
  • About Us
    • Our Mission
    • Financials
    • Venture Philanthropy
    • Supporter Spotlights
    • Leadership >
      • Board of Directors
      • Staff
  • Donate

eb simplex (EBS)

About EB Simplex

EB Simplex (EBS) is the most common form of EB. Blisters form in the epidermis, or outer layer of skin. It is caused by mutations in the genes KRT5 or KRT14, which hold the instructions to make the proteins keratin 5 and keratin 14, respectively. There are 4 major types of EBS: Localized, Dowling-Meara, Generalized, and EBS with Mottled Pigmentation. Depending on the subtype, individuals with EBS experience mild to severe symptoms. Blisters are commonly found on the hands and feet, but can be widespread.

Life with EB Simplex

Meet Anna: Click on her photo to read about her life with EBS.
Picture
Back to "What is EB?"

Other EB Subtypes

Click below to learn about the other 3 major subtypes of EB
Picture
Picture
Picture

EB Research Partnership

244 Madison Ave Ste 104
New York, NY 10016 
[email protected]
646-844-0902
Careers
​
Donor Privacy Policy

Curator Privacy Policy

Curator Terms of Use
Donate

Contact Us
​

​Our Mission

​Shop

Press
Picture

COPYRIGHT @2025 EB RESEARCH PARTNERSHIP. ALL RIGHTS RESERVED. EB RESEARCH PARTNERSHIP IS A 501(C)(3) NON PROFIT.

  • Epidermolysis Bullosa
    • What is EB?
    • Life with EB
    • Resources
  • Research
    • Our Impact
    • Scientific Advisory Board
    • Clinical Trials >
      • Filsuvez
      • Vyjuvek
      • ZEVASKYN
    • Town Halls
    • Apply for a Grant
  • Get Involved
    • Donate
    • Sponsor
    • EB Active
    • Events
    • The Effect
    • Shop
    • Give Cryptocurrency
    • Give Stocks
    • Give through Donor Advised Funds (DAF)
    • Accelerator Fund
  • Media
    • Matter of Time Film
    • Press
    • Videos
  • About Us
    • Our Mission
    • Financials
    • Venture Philanthropy
    • Supporter Spotlights
    • Leadership >
      • Board of Directors
      • Staff
  • Donate